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KMID : 1161420190220010074
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Journal of Medicinal Food
2019 Volume.22 No. 1 p.74 ~ p.80
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Hovenia dulcis Extract Attenuates High-Fat Diet-Induced Hepatic Lipid Accumulation and Hypertriglyceridemia in C57BL/6 Mice
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Park Ki-Beum
Yoon Hyo-Jung
Imm Jee-Young
Go Gwang-Woong
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Abstract
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The effects of dietary supplementation with aqueous Hovenia dulcis Thunb. extract (HDE) (20 weeks) on high-fat diet (HFD)-induced nonalcoholic fatty liver disease and dyslipidemia were evaluated in mice. Supplementation with 200 and 800?mg/kg feed HDE (HDE200 and HDE800, respectively) resulted in no significant difference in growth in the HFD-fed groups. The triglyceride (TG) levels and free fatty acids were significantly decreased, whereas high-density lipoprotein cholesterol was increased in the HDE800 group (P?
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KEYWORD
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antioxidant enzymes, hepatic lipid accumulation, Hovenia dulcis Thunb. extract, hyperlipidemia
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